Description
MG Medicals, Quality Assurance
CompositionSimeprevir 150mg
SimilaritySimeprevir 150mg
StorageRoom Temperature
MG Medicals, Briefing of Olysio 150mg 28 Capsule
Uses of Olysio 150mg 28 CapsuleOLYSIO is a hepatitis C virus (HCV) NS3/4A protease inhibitor indicated for the treatment of adults with chronic hepatitis C virus (HCV) infection:
• in combination with sofosbuvir in patients with HCV genotype 1 without
cirrhosis or with compensated cirrhosis
• in combination with peginterferon alfa (Peg-IFN-alfa) and ribavirin (RBV) in patients with HCV genotype 1 or 4 without cirrhosis or with compensated cirrhosis.
• in combination with sofosbuvir in patients with HCV genotype 1 without
cirrhosis or with compensated cirrhosis
• in combination with peginterferon alfa (Peg-IFN-alfa) and ribavirin (RBV) in patients with HCV genotype 1 or 4 without cirrhosis or with compensated cirrhosis.
Olysio 150mg 28 Capsule side reactionsRash, photosensitivity, pruritus, nausea, myalgia, dyspnea, fatigue, headache.
How to take Olysio 150mg 28 CapsuleTake OLYSIO exactly as your healthcare provider tells you to take it. Do not change your dose unless your healthcare provider tells you to.
How Olysio 150mg 28 Capsule worksSimeprevir is a direct-acting antiviral (DAA) agent against the hepatitis C virus.
MG Medicals, More Suggestion
Suggestion for Olysio 150mg 28 Capsule
- Risk of Hepatitis B Virus Reactivation: Test all patients for evidence of current or prior HBV infection before initiation of HCV treatment. Monitor HCV/HBV coinfected patients for HBV reactivation and hepatitis flare during HCV treatment and post-treatment follow-up. Initiate appropriate patient management for HBV infection as clinically indicated.
- Serious Symptomatic Bradycardia When Co-administered with Sofosbuvir and Amiodarone: Serious symptomatic bradycardia may occur in patients taking amiodarone with sofosbuvir in combination with OLYSIO, particularly in patients also receiving beta blockers, or those with underlying cardiac comorbidities and/or advanced liver disease.
- Co-administration of amiodarone with OLYSIO in combination with sofosbuvir is not recommended. In patients without alternative treatment options, cardiac monitoring is recommended.
- Serious photosensitivity reactions have been observed during OLYSIO combination therapy. Use sun protection measures and limit sun exposure during OLYSIO combination therapy. Consider discontinuation if a photosensitivity reaction occurs.
- Rash has been observed during OLYSIO combination therapy. Discontinue OLYSIO if severe rash occurs.
MG Medicals, Tips & Warnings
Alcohol
There is no significant data. Please consult your doctor.
Pregnancy
WEIGH RISKS VS BENEFITS
Olysio should not be taken if you are pregnant or plan to become pregnant. It is not known if OLYSIO will harm your unborn baby.
Lactation
WEIGH RISKS VS BENEFITS
If you are breastfeeding. It is not known if OLYSIO passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with OLYSIO.
Driving
There is no significant data. Please consult your doctor.
Kidney
There is no significant data. Please consult your doctor.
Liver
caution
Monitor LFTs before and during therapy; discontinue if elevated bilirubin and transaminases, or signs/symptoms of hepatic decompensation develop. Moderate or severe hepatic impairment: not recommended.
MG Medicals, If miss a dose
Do not take two doses of OLYSIO at the same time to make up for a missed dose.
Disclaimer
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