Yervoy 50mg 1 Injection

Vial per box: 1;
Manufacturer: BMS

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Description

MG Medicals, Quality Assurance

CompositionIpilimumab 50 mg
SimilarityIpilimumab 50 mg
UsageThere is no data.
StorageCold chain shipment
CautionThere is no data.

MG Medicals, Briefing of Yervoy 50mg 1 Injection

Uses of Yervoy 50mg 1 InjectionUses of Yervoy 50mg 1 Injection
YERVOY is indicated for the treatment of advanced (unresectable or metastatic) melanoma in adults.
Yervoy 50mg 1 Injection side reactionsYervoy 50mg 1 Injection side reactions
Fatigue, diarrhea, pruritus, rash, colitis, headache, weight loss, nausea, pyrexia, decreased appetite, vomiting, insomnia; immune-mediated reactions; also with nivolumab: musculoskeletal pain, abdominal pain, cough, arthralgia, dyspnea.
How to take Yervoy 50mg 1 InjectionHow to take Yervoy 50mg 1 Injection
It will be administered by a health care professional. Do not shake product. Inspect parenteral drug products visually for particulate matter and discoloration prior to administration. Discard vial if solution is cloudy, there is pronounced discoloration (solution may have pale-yellow color), or there is foreign particulate matter other than translucent-towhite, amorphous particles.
How Yervoy 50mg 1 Injection worksHow Yervoy 50mg 1 Injection works
CTLA-4 is a negative regulator of T-cell activity. Ipilimumab is a monoclonal antibody that binds to CTLA-4 and blocks the interaction of CTLA-4 with its ligands, CD80/CD86. Blockade of CTLA-4 has been shown to augment T-cell activation and proliferation, including the activation and proliferation of tumor infiltrating T-effector cells. Inhibition of CTLA-4 signaling can also reduce T-regulatory cell function, which may contribute to a general increase in T cell responsiveness, including the anti-tumor immune response.

MG Medicals, More Suggestion

Suggestion for Yervoy 50mg 1 Injection

  • Severe and fatal immune-mediated adverse reactions can develop. Permanently discontinue therapy and initiate systemic high-dose corticosteroids for severe, persistent, or recurring immune-mediated reactions.
  • Withhold dose for moderate immune-mediated adverse reactions until return to baseline, improvement to mild severity, or complete resolution, and patient is receiving <7.5mg prednisone or equivalent per day. Monitor for enterocolitis, hepatitis, dermatitis, neuropathy, endocrinopathy, and others including ocular manifestations; perform clinical chemistries including LFTs, ACTH levels, and thyroid tests at baseline and before each dose.
  • Monitor for infusion reactions; discontinue if severe or life-threatening; interrupt or slow infusion rate if mild or moderate.
  • Give steroid eye drops if uveitis, iritis, or episcleritis develops (may need systemic treatment if a Vogt-Koyanagi-Harada-like syndrome develops); permanently discontinue if unresponsive to local therapy. Moderate or severe hepatic impairment.

MG Medicals, Tips & Warnings

alcohol
Alcohol
There is no significant data. Please consult your doctor.
pregnancy
Pregnancy
WEIGH RISKS VS BENEFITS
Females of reproductive potential should use effective contraception during and for 3 months after final dose.
lactation
Lactation
WEIGH RISKS VS BENEFITS
For Nursing mother it is not recommended
driving
Driving
YERVOY has minor influence on the ability to drive and use machines. Because of potential adverse reactions such as fatigue (see section 4.8), patients should be advised to use caution when driving or operating machinery until they are certain that ipilimumab does not adversely affect them.
kidney
Kidney
There is no significant data. Please consult your doctor.
liver
Liver
There is no significant data. Please consult your doctor.

MG Medicals, If miss a dose

If you miss a dose of Yervoy, please contact your doctor.

Disclaimer

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